IUVA Education Resource Center

Air Disinfection

My Guiding Principles

Focus will be on Evidence-based performance studies; equipment assessments; scientific explanations of air disinfection methods; articles on the practice of decontaminating indoor environments to reduce airborne contamination. Identifying and prioritizing Information related to standards and their development. Will select from leading journals based on relevance and technical content. Bibliographies will be assembled, including seminal historical works as well as recent publications. Performance of air disinfection systems will be a priority. Vendor materials will be addressed anonymously only if they contain results from independent certified laboratories.

Wladyslaw Kowalski, Chief Scientist, SanUVox holds a PhD in Architectural Engineering from The Pennsylvania State University. Dr Kowalski has authored numerous articles on airborne disease control technologies including the widely cited Ultraviolet Germicidal Irradiation Handbook. He was previously chairman of the Air Treatment Group of IUVA and works on UV standards in collaboration with ASHRAE, ASTM, and other professional societies. He also serves on the Underwriters Laboratories UL 8800 Photobiological Safety Committee.

Documents & Resources

Sub-topicTitleAuthorCommentsSourceDateLink
UV ModelingA quantitative method of determining the lethal effect of ultraviolet light on bacteria suspended in airSharp DG

Methodology

J Bact 35:589-5991938
UV StandardsA standard method of quantifying the output of UV lampsSasges, M, A vanderPool, A Voronov and J Robinson

Standard Method

IUVA/IOA Joint Congress, International Ultraviolet Association2007
UV rate constant data - BacteriaAbiotic and sublethal effects of ultraviolet radiation on microorganismsHollaender, A

Contains valid UV k data

Aerobiol 17: 156-1651942
UV rate constant data - VirusAbsorption spectra of nucleotides, polynucleotides, and nucleic acids in the far ultravioletVoet, D, Walter, B, Gratzer, R, A, Cox, Paul, Doty

Contains valid UV k data

Biopolymers, 13:193-2081963
UV StandardsAccurate measurement of UV lamp outputSasges, M and J Robinson

Lamp output measurements

IUVA News 73: 21-252005
UV PerformanceAdvantages of bactericidal ultraviolet radiation in air conditioning systemsRentschler HC, Nagy R

Historical Air Disinfection & Cooling Coil document

HPAC 12:127-1301940
UV rate constant data - BacteriaAerosols of Mycoplasmas, L forms, and bacteria: Comparison of particle size, viability, and lethality of ultraviolet radiationKundsin RB

Contains valid UV k data

Applied Microbiology 161:143-1461968
UV applicationsAirborne spread of measles in a suburban elementary schoolRiley, EC, G Murphy and RL Riley

Epidemiology study

Am J Epidemiol 1075: 421-4321978
UV PerformanceApplications of Germicidal, Erythemal and Infrared EnergyLuckiesh M

Contains valid UV k data

New York: D Van Nostrand Co1946
UV rate constant data - BacteriaBactericidal action of ultraviolet radiation on air-borne microorganismsRentschler HC, Nagy R

Contains valid UV k data

J Bacteriol 44:85-941942
UV rate constant data - BacteriaBactericidal effect of ultraviolet radiationRentschler HC, Nagy R, Mouromseff G

Contains valid UV k data

J Bacteriol 42:745-7741941
UV rate constant data - BacteriaBactericidal irradiation of air, physical factorsWells WF

Contains valid UV k data

J Franklin Inst 229:347-3721940
UV ModelingBioassay and dose measurement in UV disinfectionQualls RG, Johnson JD

UV Dose measurement data

Appl Microb 453:872-8771983
UV PerformanceBiological Inactivation Efficiency by HVAC In-Duct Ultraviolet Light Systems: Steril-Aire, IncEPA

Contains valid UV k data

Environmental Protection Agency2006
UV rate constant data - BacteriaCharacterization of Mycoplasma aerosols as to viability, particle size, and lethality of ultraviolet radiationKundsin RB

Contains valid UV k data

J Bacteriol 913:942-9441966
UV PerformanceClearing the air: The theory and application of ultraviolet disinfectionRiley RL, Nardell EA

Performance theory

Am Rev Resp Dis 139:1286-12941989
UV PerformanceDefining the Effectiveness of UV Lamps Installed in Circulating Air DuctworkVan Osdell, D and K Foarde

Modeling effectiveness

Arlington, VA, Air-Conditioning and Refrigeration Technology Institute2002
UV ModelingDesign and optimization of UVGI air disinfection systems Doctoral Dissertation, The Pennsylvania State UniversityKowalski, WJ

Design & optimization

2001
UV PerformanceDevelopment of a protocol for the determination of the ultraviolet sensitivity of microorganisms suspended in airKe, Q, S Craik, M El-Din and J Bolton

Contains valid UV k data & a test protocol

Aerosol Sci Technol 434: 284-2892009
UV RH data - SporesEffect of relative humidity on the aerodynamic diameter and respiratory deposition of fungal sporesReponen, T, K Willeke, V Ulevicius, A Reponen and S Grinshpun

RH data

Atmos Environ 30: 3967-39741996
UV rate constant data - BacteriaEffect of relative humidity on the inactivation of airborne Serratia marcescens by ultraviolet radiationRiley RL, Kaufman JE

Contains valid UV k data

Applied Microbiology 236:1113-11201972
UV rate constant data - VirusEffect of ultraviolet germicidal irradiation of the air on the incidence of upper respiratory tract infections in kittens in a nurseryJaynes, RA, MC Thompson and MA Kennedy

Outcomes based results

J Am Vet Med Assoc 2579: 929-9322020
UV rate constant data - BacteriaEffect of ultraviolet germicidal irradiation on viral aerosolsWalker CM, Ko G

Contains valid UV k data

Environ Sci Technol 4115:5460-54652007
UV PerformanceEffectiveness of a shielded ultraviolet C air disinfection system in an inpatient pharmacy of a tertiary care children’s hospitalGuimera, D, J Trzil, J Joyner and ND Hysmith

Concentration reduction data

Am J Infect Control 462: 223-2252018
UV PerformanceEffectiveness of a shielded ultraviolet C air disinfection system in an inpatient pharmacy of a tertiary care children’s hospitalGuimera, D, J Trzil, J Joyner and ND Hysmith

Concentration reduction data

Am J Infect Control 462: 223-2252018
UV rate constant data - BacteriaEffects of relative humidity on the ultraviolet induced inactivation of airborne bacteriaPeccia J, Werth HM, Miller S, Hernandez M

Contains valid UV k & RH data

Aerosol Sci & Technol 35:728-7402001
UV rate constant data - BacteriaEfficacy of ultraviolet germicidal irradiation of upper-room air in inactivating airborne bacterial spores and mycobacteria in full-scale studiesXu, P, J Peccia, P Fabian, JW Martyny, KP Fennelly, M Hernandez and SL Miller

Contains valid UV k data

Atmos Environ 37: 405-4192003
UV PerformanceEvaluation of multiple fixed in-room air cleaners with ultraviolet germicidal irradiation, in high-occupancy areas of selected commercial indoor environmentsLee, L D, G Delclos, ML Berkheiser, MT Barakat and PA Jensen

In-place testing of air disinfection

J Occup Environ Hyg 191: 67-772022
UV rate constant data - BacteriaFactors affecting the viability of air-borne bacteria: IV The inactivation and reactivation of air-borne Serratia marcescens by ultraviolet and visible lightWebb SJ

Contains valid UV k data

Can J Microbiol 7:607-6191961
UV rate constant data - BacteriaFactors affecting the viability of air-borne bacteria: V The effect of desiccation on some metabolic systems of Escherichia coliWebb SJ

Contains valid UV k data

Can J Microbiol 7:621-6321961
UV PerformanceFeasibility Study of Germicidal UV Lamps for Air Disinfection in Simulated Patient Care RoomsKethley TW

Historical Air Disinfection Test

San Francisco, CA: American Public Health Association1973
UV PerformanceImpact of UVC-sustained recirculating air filtration on airborne bacteria and dust in a pig facilityEisenloffel, L, T Reutter, M Horn, S Schlegel, U Truyen and S Speck

Contains valid UV & filtration data

PLoS One 1411: e02250472019
UV rate constant data - VirusInactivation of airborne viruses by ultraviolet irradiationJensen MM

Contains valid UV k data

Applied Microbiology 125:418-4201964
UV rate constant data - VirusInactivation of poxviruses by upper-room UVC light in a simulated hospital room environmentMcDevitt, JJ, DK Milton, SN Rudnick and MW First

Contains valid UV k data

PLoS One 39: e31862008
UV rate constant data - VirusInactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoVDarnell MER, Subbarao K, Feinstone SM, Taylor DR

Contains valid UV k data

J Virol Meth 121:85-912004
UV rate constant data - VirusInactivation of virus-containing aerosols by ultraviolet germicidal irradiationTseng C-C, Li C-S

Contains valid UV k data

Aerosol Sci Technol 391136-11422005
UV rate constant data - BacteriaInfluence of relative humidity on particle size and UV sensitivity of Serratia marcescens and Mycobacterium bovis BCG aerosolsKo G, First MW, Burge HA

Contains valid UV k data & RH effects

Tuber Lung Dis 804/5:217-2282000
UV rate constant data - VirusInfluence of relative humidity on the photochemistry of DNA filmsRahn RO, Hosszu JL

Contains valid UV & RH effects data

Biochim Biophys Acta 190:126-1311969
UV PerformanceKilling air-borne microorganisms with germicidal energyLuckiesh M, Taylor AH, Knowles T

Contains valid UV k data

Journal of the Franklin Institute Oct :267-2901947
UV ModelingLighting Handbook: Reference & Application IESNA HB-9-2000IESNA

Historic IESNA refrence book

New York: Illumination Engineering Society of North America2000
UV ModelingMathematical modeling of UVGI for air disinfectionKowalski WJ, Bahnfleth WP, Witham DL, Severin BF, Whittam TS

Modeling document

Quantitative Microbiology 23:249-2702000
UV rate constant data - BacteriaMethod of Testing Ultraviolet Lamps for Use In HVAC&R Units of Air Ducts to Inactivate Microorganisms on Irradiated SurfacesASHRAE

Proposed method of testing

ASHRAE2014
UV ModelingMolecular Photobiology: Inactivation and RecoverySmith KC, Hanawalt PC

Contains valid UV k data

New York: Academic Press1969
UV rate constant data - BacteriaPhotoreactivation and ultraviolet inactivation of Mycobacteria in air, MS ThesisGillis HL

Contains valid UV k data

Atlanta, Georgia Technical University1974
UV rate constant data - BacteriaPhotoreactivation in Airborne Mycobacterium parafortuitumPeccia J, Hernandez M

Contains valid UV k data

Appl and Environ Microbiol 67:4225-42322001
UV ModelingProposed method for measurement of the output of monochromatic 254 nm low pressure UV lampsLaval, O, B Dussert, C Howarth, K Platzer, M Sasges, J Muller, E Whitby, R Stowe, V Adam, D Witham, S Engel, P Posey and A vandePol

Contains valid UV k data

IUVA News 101: 14-172008
UV SafetyProtection against lethal damage induced by ultraviolet radiationSchoenborn, HW

UV safety document

J Eukaryotic Microbiol 32: 97-991956
UV rate constant data - VirusPyrimidine dimers in ultraviolet-irradiated DNA’sSetlow RB, Carrier WL

Contains valid UV k data

J Mol Biol 17:237-254 missing 250-2541966
UV rate constant data - BacteriaRadiation BiologyCasarett AP

Historical Reference with valid UV k data

Englewood: Prentice-Hall1968
UV rate constant data - VirusRadiation Biology Volume IIZelle MR, Hollaender A

Historical document

New York: McGraw-Hill1955
UV PerformanceReduction of Particles in the Operating Room Using Ultraviolet Air Disinfection and Recirculation UnitsCurtis, GL, M Faour, M Jawad, AK Klika, WK Barsoum and CA Higuera

Contains valid UV k data & particle data

J Arthroplasty 337S: S196-S2002018
UV rate constant data - BacteriaSize and UV germicidal irradiation susceptibility of Serratia marcescens when aerosolized from different suspending mediaLai KM, Burge, H, and First, MW

Contains valid UV k data

Appl Environ Microbiol 704:2021-20272004
UV rate constant data - BacteriaStability of disseminated aerosols of Pastuerella tularensis subjected to simulated solar radiations at various humiditiesBeebe JM

Contains valid airborne UV k data

Journal of Bacteriology 78:18-241959
UV PerformanceSterilization efficacy of ultraviolet irradiation on microbial aerosols under dynamic airflow by experimental air conditioning systemsNakamura H

Contains valid UV k airborne data

Bull Tokyo Med Dent Univ 342:25-401987
UV rate constant data - BacteriaThe effects of ultraviolet light on bacteria suspended in airSharp G

Contains valid UV k data

J Bact 38:535-5471940
UV rate constant data - VirusThe inactivation of poliovirus in aerosolsde Jong JC, KC Winkler

Contains valid UV k data

Journal of Hygiene 66:557-5651968
UV rate constant data - BacteriaThe influence of relative humidity on the UV susceptibility of airborne gram negative bacteriaFletcher, L

Contains valid UV k & RH effects data

IUVA News 61: 12-192004
UV rate constant data - VirusThe physical state of viral nucleic acid and the sensitivity of viruses to ultraviolet lightRauth AM

Contains valid UV k data

Biophysical Journal 5:257-2731965
UV rate constant data - VirusThe ultraviolet susceptibility of aerosolised microorganisms and the role of photoreactivation; 2003; ViennaFletcher LA, Noakes CJ, Beggs CB, Sleigh PA, Kerr KG

Contains valid UV k data

IUVA2003
UV PerformanceUltra-violet Irradiation as a Means of Disinfection of AirHollaender, A

Historical document on air disinfection

Am J Public Health Nations Health 338: 980-9841943
UV PerformanceUltra-violet Irradiation as a Means of Disinfection of AirHollaender, A

Historical document on air disinfection

Am J Public Health Nations Health 338: 980-9841943
UV rate constant data - VirusUltraviolet Germicidal Irradiation Handbook: UVGI for Air and Surface DisinfectionKowalski, WJ

Contains valid UV k data

New York, Springer2009
UV rate constant data - VirusUltraviolet-induced damage to DNA independent of molecular weightScholes CP, Hutchinson F, Hales HB

Contains valid UV k data

J Mol Biol 24:471-4741967
UV rate constant data - BacteriaUse of ultraviolet irradiation in a room air conditioner for removal of bacteriaHarstad JB, HM Decker, AGWedum

Historical document on cooling coil UV

American Industrial Hygiene Association Journal 2:148-1511954
UV rate constant data - BacteriaUV dose required to achieve incremental log inactivation of bacteria, protozoa and virusesChevrefils G, Caron E, Wright H, Sakamoto G, Payment P, Barbeau B, Cairns B

Summary of UV k data from 2006

IUVA News 81:38-452006
UV rate constant data - VirusUV Light Inactivation of Bacterial Biothreat AgentsRose, LJ and H O'Connell

Contains valid UV k data

Appl Environ Microbiol 759: 2987-29002009
UV rate constant data - BacteriaUV radiators in humidifying units and air channels of air conditioning systems in hospitalsGrun L, Pitz N

Historical data on cooling coil UV

Zbl Bakt Hyg B159:50-601974
UV rate constant data - BacteriaUV-induced inactivation rates for airborne Mycobacterium bovis BCGPeccia J, and Hernandez, M

Contains valid UV k data

J Occup Environ Hyg 17:430-4352002
UV rate constant data - BacteriaUVGI Catalog and Design GuidePhilips

Historical Catalog

Netherlands: Catalog No UDC 628.91985
UV rate constant data - VirusViricidal activity of open airBenbough JE, AM Hood

Contains valid UV k data in air

Journal of Hygiene 69:619-6261971